THE CHEMICAL-ENZYMATIC SYNTHESIS OF A CARBON GLYCOSIDE OF N-ACETYL NEURAMINIC ACID

被引：48

作者：

NAGY, JO

BEDNARSKI, MD

机构：

[1] UNIV CALIF BERKELEY,DEPT CHEM,BERKELEY,CA 94720

[2] LAWRENCE BERKELEY LAB,CTR ADV MAT,BERKELEY,CA 94720

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 32期

关键词：

CARBON GLYCOSIDE; NEURAMINIC ACID; RADICAL COUPLING; ENZYMATIC; VIRAL INHIBITORS;

D O I：

10.1016/0040-4039(91)80598-Z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A C-glycoside of neuraminic acid (NeuAc) has been synthesized by a combined use of an enzyme catalyzed aldol reaction and a tin mediated radical coupling reaction.

引用

页码：3953 / 3956

页数：4

共 32 条

[11] GIESE B, 1983, ANGEW CHEM INT EDIT, V22, P622, DOI 10.1002/anie.198306221
[12] CHEMISTRY OF ORGANO-SILICON COMPOUNDS .194. HIGHLY STEREOSELECTIVE C-ALLYLATION OF GLYCOPYRANOSIDES WITH ALLYLSILANES CATALYZED BY SILYL TRIFLATE OR IODOSILANE
HOSOMI, A
SAKATA, Y
SAKURAI, H
[J]. TETRAHEDRON LETTERS, 1984, 25 (22) : 2383 - 2386
[13] ONE ELECTRON C-C BOND FORMING REACTIONS VIA ALLYLSTANNANES - SCOPE AND LIMITATIONS
KECK, GE
ENHOLM, EJ
YATES, JB
WILEY, MR
[J]. TETRAHEDRON, 1985, 41 (19) : 4079 - 4094
[14] ENZYMES IN CARBOHYDRATE SYNTHESIS - N-ACETYLNEURAMINIC ACID ALDOLASE CATALYZED-REACTIONS AND PREPARATION OF N-ACETYL-2-DEOXY-D-NEURAMINIC ACID-DERIVATIVES
KIM, MJ
HENNEN, WJ
SWEERS, HM
WONG, CH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (19) : 6481 - 6486
[15] MCGUIRE EJ, 1976, BIOL ROLES SIALIC AC
[16] MESMAEKER AD, 1989, TETRAHEDRON LETT, V30, P6307
[17] MESMAEKER AD, 1989, TETRAHEDRON LETT, V30, P6311
[18] MIRELMAN D, 1986, WILEY SERIES ECOLOGI
[19] NAGY JB, UNPUB
[20] STEREOSELECTIVE ACCESS TO ALPHA-D-FRUCTOFURANOSYL AND BETA-D-FRUCTOFURANOSYL C-GLYCOSIDES
NICOTRA, F
PANZA, L
RUSSO, G
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (25) : 5627 - 5630

← 1 2 3 4 →