CONFIDENCE-INTERVALS FOR A BINOMIAL PROPORTION

被引:347
作者
VOLLSET, SE
机构
[1] Section for Medical Informatics and Statistics, University of Bergen, Armauer Hansen Building — Haukeland Hospital, Bergen
关键词
D O I
10.1002/sim.4780120902
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Thirteen methods for computing binomial confidence intervals are compared based on their coverage properties, widths and errors relative to exact limits. The use of the standard textbook method, x/n +/- 1.96 square-root[(x/n) (1 - x/n)/n], or its continuity corrected version, is strongly discouraged. A commonly cited rule of thumb stating that alternatives to exact methods may be used when the estimated proportion p is such that np and n(1 - p) both exceed 5 does not ensure adequate accuracy. Score limits are easily calculated from closed form solutions to quadratic equations and can be used at all times. Based on coverage functions, the continuity corrected score method is recommended over exact methods. Its conservative nature should be kept in mind, as should the wider fluctuation of actual coverage that accompanies omission of the continuity correction.
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页码:809 / 824
页数:16
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