ENHANCEMENT BY ACIDIC PHOSPHOLIPIDS OF THE RATE OF SYNTHESIS OF N-ACETYLGLUCOSAMINYLPYROPHOSPHORYLDOLICHOL FROM DOLICHOL PHOSPHATE IN RAT LUNG MEMBRANES

被引：19

作者：

PLOUHAR, PL

BRETTHAUER, RK

机构：

[1] Department of Chemistry, University of Notre Dame, Notre Dame

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 90卷 / 04期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0006-291X(79)91162-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The rate of synthesis of N-acetylglucosaminylpyrophosphoryldolichol in dense membrane fractions of rat lung microsomes supplemented with dolichol phosphate was enhanced by the addition of phospholipids. Phosphatidylglycerol alone was more effective than a phospholipid mixture. Only phosphatidylinositol of other phospholipids tested significantly enhanced the reaction rate. The effect was more apparent in dense membrane fractions (rough endoplasmic reticulum) which have a low total phospholipid and phosphatidylglycerol content. © 1979.

引用

页码：1186 / 1193

页数：8

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