PARAGANGLIOMA OF THE LARYNX - A CRITICAL-REVIEW OF THE LITERATURE

被引:76
作者
BARNES, L
机构
[1] University of Pittsburgh School of Medicine and Division of Anatomic Pathology, Presbyterian University Hospital and Montefiore University Hospital, Pittsburgh, PA
来源
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES | 1991年 / 53卷 / 04期
关键词
PARAGANGLIOMA; LARYNX; NEUROENDOCRINE NEOPLASM;
D O I
10.1159/000276221
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The clinicopathologic features of two cases of paragangliomas of the larynx are presented along with immunohistochemical, ultrastructural and DNA image analysis. The world literature is also critically reviewed in order to develop a more accurate clinicopathologic profile of the tumor. The results indicate that paragangliomas of the larynx occur in patients averaging 47 years of age and are 3 times more common in women. Most (82%) arise from the supraglottic larynx and manifest clinically as hoarseness. They are typically benign and rarely functional. Almost all alleged malignant paragangliomas of the larynx are in reality atypical carcinoids that have been misdiagnosed. Features that distinguish paragangliomas from other similar tumors are discussed.
引用
收藏
页码:220 / 234
页数:15
相关论文
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