ESTIMATING THE PROPORTION OF IMMUNES IN CENSORED SAMPLES - A SIMULATION STUDY

被引：15

作者：

GHITANY, ME ^{[1
]}

MALLER, R ^{[1
]}

ZHOU, S ^{[1
]}

机构：

[1] UNIV WESTERN AUSTRALIA,DEPT MATH,NEDLANDS,WA 6009,AUSTRALIA

来源：

STATISTICS IN MEDICINE | 1995年 / 14卷 / 01期

关键词：

D O I：

10.1002/sim.4780140106

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We review currently known results concerning the estimation of an 'immune' or 'cured' proportion, and testing for the presence of immunes, in censored survival data, suggesting that a firm theoretical foundation now exists for analysis. Two types of estimators, parametric and non-parametric, are discussed and compared with respect to their theoretical properties, and, by simulation, with respect to their small sample behaviour. Both estimators have advantages and drawbacks, but together provide powerful tools for the perceptive analysis of survival data with, or even without, immune individuals.

引用

页码：39 / 49

页数：11

共 20 条

[11] NONPARAMETRIC-ESTIMATION FROM INCOMPLETE OBSERVATIONS
KAPLAN, EL
MEIER, P
[J]. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1958, 53 (282) : 457 - 481
[12] Maller R., 1993, AUSTR J STATISTICS, V35, P5
[13] THE PROBABILITY THAT THE LARGEST OBSERVATION IS CENSORED
MALLER, RA
ZHOU, S
[J]. JOURNAL OF APPLIED PROBABILITY, 1993, 30 (03) : 602 - 615
[14] ESTIMATING THE PROPORTION OF IMMUNES IN A CENSORED SAMPLE
MALLER, RA
ZHOU, S
[J]. BIOMETRIKA, 1992, 79 (04) : 731 - 739
[15] Maller RA, 1992, STATISTICS, V23, P321, DOI [10.1080/02331889208802379, DOI 10.1080/02331889208802379]
[16] McCullagh P., 1983, GEN LINEAR MODELS
[17] A SIMPLEX-METHOD FOR FUNCTION MINIMIZATION
NELDER, JA
MEAD, R
[J]. COMPUTER JOURNAL, 1965, 7 (04) : 308 - 313
[18] A COMPARISON OF TESTS OF THE DIFFERENCE IN THE PROPORTION OF PATIENTS WHO ARE CURED
SPOSTO, R
SATHER, HN
BAKER, SA
[J]. BIOMETRICS, 1992, 48 (01) : 87 - 99
[19] ZHOU S, 1992, 11 U W AUSTR DEP MAT
[20] 1990, NAG FORTRAN LIBRARY, V7

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