2-AMINO-2-OXAZOLINES .3. SYNTHESIS, STRUCTURE, AND PRELIMINARY PHARMACOLOGICAL EVALUATION OF CYCLOADDITION COMPOUNDS WITH UNSATURATED CARBOXYLIC ESTERS

被引：12

作者：

FORFAR, I ^{[1
]}

JARRY, C ^{[1
]}

LEGER, JM ^{[1
]}

CARPY, A ^{[1
]}

机构：

[1] UNIV BORDEAUX 2,FAC SCI PHARMACEUT,CNRS,URA 605,F-33076 BORDEAUX,FRANCE

来源：

ARCHIV DER PHARMAZIE | 1990年 / 323卷 / 11期

关键词：

D O I：

10.1002/ardp.19903231105

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The reaction of 5‐substituted 2‐amino‐2‐oxazolines with unsaturated carboxylic esters yielded 2,3,5,6‐tetrahydro‐ and 2,3‐dihydro‐7H‐oxazolo[3,2‐a]pyrimidin‐7‐ones. The structure of these compounds was established by IR‐ and NMR‐spectra and by X‐ray crystallography. They were tested for anti‐arrhythmic and hypocholesterolemic activities. Copyright © 1990 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：905 / 909

页数：5

共 20 条

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