ONLINE MEASUREMENT OF CELL MASS AND SPECIFIC GROWTH-RATE BY A LASER TURBIDITY METER COUPLED WITH DATA SMOOTHING USING A ONE-PASS METHOD

被引：7

作者：

HORIUCHI, J ^{[1
]}

KISHIMOTO, M ^{[1
]}

MOMOSE, H ^{[1
]}

机构：

[1] SCI UNIV TOKYO,DEPT BIOL SCI & TECHNOL,NODA,CHIBA 278,JAPAN

来源：

BIOTECHNOLOGY TECHNIQUES | 1994年 / 8卷 / 08期

关键词：

D O I：

10.1007/BF00152153

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A data smoothing algorithm by a one-pass method employing spline function was applied to a laser turbidity meter for on-line measurement of cell mass and specific growth rate in the culture using recombinant E. coli. The outputs from the laser turbidity meter containing noise and errors were successfully filtered by the method, leading to more reliable estimation of cell mass and specific growth rate in real time.

引用

页码：595 / 600

页数：6

共 13 条

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[12] FED-BATCH CULTURE AUTOMATED BY USES OF CONTINUOUSLY MEASURED CELL CONCENTRATION AND CULTURE VOLUME
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