EXCLUSION MAPPING IN FAMILIAL NONSPECIFIC DEMENTIA

被引：9

作者：

BROWN, J

GYDESEN, S

SORENSEN, SA

BRUN, A

DUFF, K

HOULDEN, H

FIDANI, L

KULLKARNI, S

CUMMINGS, J

GOATE, A

ROSSOR, M

HARDY, J

机构：

[1] UNIV COPENHAGEN,PANUM INST,INST MED GENET,DK-2200 COPENHAGEN,DENMARK

[2] UNIV LUND HOSP,DEPT NEUROPATHOL,S-22185 LUND,SWEDEN

[3] ST MARYS HOSP,DEPT NEUROL,LONDON W2 1PG,ENGLAND

来源：

DEMENTIA | 1993年 / 4卷 / 3-4期

关键词：

FRONTAL LOBE DEMENTIA; NONSPECIFIC DEMENTIA; PICKS DISEASE; MICROSATELLITE SEQUENCES; LINKAGE ANALYSIS;

D O I：

10.1159/000107317

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We present genetic linkage data in a large family in which non-specific dementia is inherited as an autosomal dominant trait. We have analyzed 45 highly polymorphic microsatellite sequences and excluded a quarter of the genome as the site of the pathogenic mutation in this family.

引用

页码：163 / 166

页数：4

共 45 条

[31] DINUCLEOTIDE REPEAT POLYMORPHISMS AT THE D7S435 AND D7S440 LOCI
WEBER, JL
KWITEK, AE
MAY, PE
[J]. NUCLEIC ACIDS RESEARCH, 1990, 18 (13) : 4039 - 4039
[32] WEBER JL, 1990, NUCLEIC ACIDS RES, V18, P4635, DOI 10.1093/nar/18.15.4635-a
[33] DINUCLEOTIDE REPEAT POLYMORPHISMS AT THE D16S260, D16S261, D16S265, D16S266, AND D16S267 LOCI
WEBER, JL
KWITEK, AE
MAY, PE
[J]. NUCLEIC ACIDS RESEARCH, 1990, 18 (13) : 4034 - 4034
[34] DINUCLEOTIDE REPEAT POLYMORPHISMS AT THE D11S419 AND CD3D LOCI
WEBER, JL
KWITEK, AE
MAY, PE
[J]. NUCLEIC ACIDS RESEARCH, 1990, 18 (13) : 4036 - 4036
[35] WEBER JL, 1989, AM J HUM GENET, V44, P388
[36] WEBER JL, 1990, NUCLEIC ACIDS RES, V18, P4640, DOI 10.1093/nar/18.15.4640
[37] DINUCLEOTIDE REPEAT POLYMORPHISMS AT THE D8S85, D8S87, AND D8S88 LOCI
WEBER, JL
KWITEK, AE
MAY, PE
PATTERSON, D
DRABKIN, H
[J]. NUCLEIC ACIDS RESEARCH, 1990, 18 (13) : 4038 - 4038
[38] DINUCLEOTIDE REPEAT POLYMORPHISMS AT THE D5S107, D5S108, D5S111, D5S117 AND D5S118 LOCI
WEBER, JL
KWITEK, AE
MAY, PE
[J]. NUCLEIC ACIDS RESEARCH, 1990, 18 (13) : 4035 - 4035
[39] WEBER JL, IN PRESS GENOMICS
[40] WEBER JL, 1990, NUCLEIC ACIDS RES, V18, P2200

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