THE SYNTHESIS OF GAMMA-SUBSTITUTED GLUTAMIC ACIDS VIA A GLUTAMIC-ACID GAMMA-ENOLATE SYNTHON

被引：6

作者：

JOHNSTONE, ANC ^{[1
]}

LOPATRIELLO, S ^{[1
]}

NORTH, M ^{[1
]}

机构：

[1] UNIV COLL N WALES,DEPT CHEM,BANGOR LL57 2UW,GWYNEDD,WALES

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 34期

关键词：

D O I：

10.1016/S0040-4039(00)73426-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of alpha-t-butyl gamma-methyl N-Z-glutamate (4) with lithium hexamethyldisilazide results in the regiospecific formation of the gamma-anion, which reacts with electrophiles to give gamma-substituted glutamic acid derivatives.

引用

页码：6335 / 6338

页数：4

共 21 条

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