SYNTHESIS OF NON-PROTEINOGENIC AMINO-ACIDS WITH 3 CHIRAL CENTERS

被引：28

作者：

BOWLER, AN ^{[1
]}

DOYLE, PM ^{[1
]}

HITCHCOCK, PB ^{[1
]}

YOUNG, DW ^{[1
]}

机构：

[1] UNIV SUSSEX,SCH CHEM & MOLEC SCI,BRIGHTON BN1 9QJ,E SUSSEX,ENGLAND

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 23期

关键词：

PYROGLUTAMATE; IMINE; AMINO ACID; NON-PROTEINOGENIC; DIASTEREOSELECTIVE;

D O I：

10.1016/S0040-4039(00)78817-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of activated imines with the lactam enolate of the protected pyroglutamic ester (1) has been used to prepare optically pure derivatives of amino acids containing three chiral centres.

引用

页码：2679 / 2682

页数：4

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