SYNTHESIS OF TROGER BASE ANALOGS DERIVED FROM 3-AMINOACRIDINE AND 10-AMINOBENZO[B][1,7]PHENANTHROLINE

被引：48

作者：

SALEZ, H ^{[1
]}

WARDANI, A ^{[1
]}

DEMEUNYNCK, M ^{[1
]}

TATIBOUET, A ^{[1
]}

LHOMME, J ^{[1
]}

机构：

[1] UNIV GRENOBLE 1,CNRS,ETUD DYNAM & STRUCT SELECT LAB,F-38041 GRENOBLE 9,FRANCE

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 08期

关键词：

D O I：

10.1016/0040-4039(95)00004-V

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The heterocyclic aromatic amines 10-aminobenzo[b][1,7]phenanthroline 1 and 3-aminoacridine 2 react regioselectivety with formaldehyde in acidic medium to yield the Troger's base analogs 7 and 8.

引用

页码：1271 / 1274

页数：4

共 20 条

[1] CHEMISTRY OF SYNTHETIC RECEPTORS AND FUNCTIONAL-GROUP ARRAYS .10. ORDERLY FUNCTIONAL-GROUP DYADS - RECOGNITION OF BIOTIN AND ADENINE-DERIVATIVES BY A NEW SYNTHETIC HOST [J].

ADRIAN, JC ;

WILCOX, CS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (20) :8055-8057

[2] CHEMISTRY OF SYNTHETIC RECEPTORS AND FUNCTIONAL-GROUP ARRAYS .15. EFFECTS OF ADDED WATER ON THERMODYNAMIC ASPECTS OF HYDROGEN-BOND-BASED MOLECULAR RECOGNITION IN CHLOROFORM [J].

ADRIAN, JC ;

WILCOX, CS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (02) :678-680

[3] THE CHEMISTRY OF SYNTHETIC RECEPTORS AND FUNCTIONAL GROUP ARRAYS .19. GENERAL EFFECTS OF BINDING-SITE WATER EXCLUSION ON HYDROGEN-BOND BASED MOLECULAR RECOGNITION SYSTEMS - A CLOSED BINDING-SITE IS LESS AFFECTED BY ENVIRONMENTAL-CHANGES THAN AN OPEN SITE [J].

ADRIAN, JC ;

WILCOX, CS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (04) :1398-1403

[4]

BAGULEY BC, 1991, ANTI-CANCER DRUG DES, V6, P1

[5] ISOLATION OF A HIGHLY FUNCTIONALIZED TROGER BASE DERIVATIVE VIA A NOVEL REACTION [J].

BECKER, DP ;

FINNEGAN, PM ;

COLLINS, PW .

TETRAHEDRON LETTERS, 1993, 34 (12) :1889-1892

[6] CLATHRATE FORMATION WITH TROEGER BASE ANALOGS [J].

BOND, DR ;

SCOTT, JL .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1991, (01) :47-51

[7]

CERRADA ML, 1993, AN QUIM-INT, V89, P141

[8]

CERRADA ML, 1993, J CHEM SOC CHEM COMM, V23, P1713

[9]

COPPEL Y, IN PRESS J BIOMOL ST

[10] MOLECULAR RECOGNITION IN AQUEOUS-MEDIA - CONFORMATIONALLY RESTRICTED WATER-SOLUBLE CYCLOPHANES DERIVED FROM 6H,12H-5,11-METHANODIBENZO[B,F][1,5]DIAZOCINE [J].

COWART, MD ;

SUCHOLEIKI, I ;

BUKOWNIK, RR ;

WILCOX, CS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (18) :6204-6210

← 1 2 →