ENOLIC RADICAL DERIVED FROM ACETIC-ACID - A USEFUL RADICAL ALTERNATIVE TO ACETATE ENOLATE IN MICHAEL-TYPE REACTIONS

被引：16

作者：

FOUBELO, F ^{[1
]}

LLORET, F ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,APDO 99,E-03080 ALICANTE,SPAIN

来源：

TETRAHEDRON | 1993年 / 49卷 / 37期

关键词：

D O I：

10.1016/S0040-4020(01)81929-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of iodoacetic acid 1 with tributyltin chloride and sodium borohydride in the presence of different electrophilic olefins 2 (methyl, allyl or tert-butyl acrylates, N,N-dimethyl or N,N-di-iso-propyl acrylamides, acrylonitrile, methyl methacrylate, methacrylonitrile and 1,1-dichloroethylene) and AIBN as an initiator yields, after treatment with aqueous sodium fluoride, the corresponding products 3 through a radical Michael-type process.

引用

页码：8465 / 8470

页数：6

共 21 条

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