ANCHOR FOR ONE-STEP RELEASE OF 3'-AMINOOLIGONUCLEOTIDES FROM A SOLID SUPPORT

被引：13

作者：

GRYAZNOV, SM ^{[1
]}

LETSINGER, RL ^{[1
]}

机构：

[1] NORTHWESTERN UNIV,DEPT CHEM,EVANSTON,IL 60208

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 08期

关键词：

OLIGONUCLEOTIDES; AMINES; SOLID SUPPORT TETHER;

D O I：

10.1016/S0040-4039(00)91769-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A linker is described that permits covalently bound aminooligonucleotides to be liberated from a solid support by one step treatment with ammonium hydroxide.

引用

页码：1261 / 1264

页数：4

共 5 条

[1] OXALYL-CPG - A LABILE SUPPORT FOR SYNTHESIS OF SENSITIVE OLIGONUCLEOTIDE DERIVATIVES
ALUL, RH
SINGMAN, CN
ZHANG, GR
LETSINGER, RL
[J]. NUCLEIC ACIDS RESEARCH, 1991, 19 (07) : 1527 - 1532
[2] SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING AMINODEOXYTHYMIDINE UNITS
GRYAZNOV, SM
LETSINGER, RL
[J]. NUCLEIC ACIDS RESEARCH, 1992, 20 (13) : 3403 - 3409
[3] A NEW APPROACH TO SYNTHESIS OF OLIGONUCLEOTIDES WITH 3'PHOSPHORYL GROUPS
GRYAZNOV, SM
LETSINGER, RL
[J]. TETRAHEDRON LETTERS, 1992, 33 (29) : 4127 - 4128
[4] JASTROFF B, 1969, TETRAHEDRON LETT, P2543
[5] NUCLEOTIDE CHEMISTRY .16. PHOSPHORAMIDATE ANALOGS OF OLIGONUCLEOTIDES
LETSINGE.RL
MUNGALL, WS
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1970, 35 (11) : 3800 - &

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