FREQUENCY OF POSITIVE FAMILY HISTORY IN BIPOLAR PATIENTS IN A CATCHMENT-AREA POPULATION

被引：6

作者：

ALEXANDER, JR

BENJAMIN, J

LERER, B

BARON, M

BELMAKER, RH

机构：

[1] HEBREW UNIV JERUSALEM,HADASSAH MED SCH,DEPT PSYCHIAT,IL-91010 JERUSALEM,ISRAEL

[2] BEN GURION UNIV NEGEV,SOROKA MED CTR,DIV PSYCHIAT,KUPAT HOLIM SICK FUND,IL-84105 BEER SHEVA,ISRAEL

[3] COLUMBIA UNIV,COLL PHYS & SURG,NEW YORK STATE PSYCHIAT INST,DEPT MED GENET,NEW YORK,NY 10027

[4] BEN GURION UNIV NEGEV,MINIST HLTH,BEER MENTAL HLTH CTR,DIV PSYCHIAT,IL-84105 BEER SHEVA,ISRAEL

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 1995年 / 19卷 / 03期

关键词：

EPIDEMIOLOGY; GENETICS; MANIC-DEPRESSIVE ILLNESS;

D O I：

10.1016/0278-5846(95)00018-Q

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

1. Major family studies of bipolar disorder report the frequency of affective disorder among probands' relatives, but do not usually report the frequency of a positive family history among probands. A single previous study was not population based. 2. The Division of Psychiatry of Ben Gurion University provides virtually all psychiatric services for a catchment area of 300,000 people. The authors reviewed the charts of all 236 treated bipolar I patients in 1991, and interviewed 177 of them with a modified FH-RDC. 3. 48% of probands had a family history of mental illness. 4. However, the present methods of ascertainment may have been insufficiently sensitive.

引用

页码：367 / 373

页数：7

共 12 条

[1]

ANDREASEN NC, 1986, ARCH GEN PSYCHIAT, V43, P421

[2]

BARON M, 1992, GENETIC RES PSYCHIAT, P1

[3] CHROMOSOME-18 DNA MARKERS AND MANIC-DEPRESSIVE ILLNESS - EVIDENCE FOR A SUSCEPTIBILITY GENE [J].