MOENOMYCIN-A - REACTIONS AT THE LIPID PART - NEW STRUCTURE-ACTIVITY RELATIONS

被引：23

作者：

MARZIAN, S

HAPPEL, M

WAGNER, U

MULLER, D

WELZEL, P

FEHLHABER, HW

STARK, A

SCHUTZ, HJ

MARKUS, A

LIMBERT, M

VANHEIJENOORT, Y

VANHEIJENOORT, J

机构：

[1] RUHR UNIV BOCHUM, FAK CHEM, D-44780 BOCHUM, GERMANY

[2] HOECHST AG, D-65926 FRANKFURT, GERMANY

[3] UNIV PARIS 11, ORSAY, FRANCE

来源：

TETRAHEDRON | 1994年 / 50卷 / 18期

关键词：

D O I：

10.1016/S0040-4020(01)80688-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methods for the removal and the oxidation of the lipid moiety of the antibiotic moenomycin A have been studied. Combined with biochemical studies,the results demonstrate that antibiotic activity is closely related with the integrity of the lipid unit.

引用

收藏

页码：5299 / 5308

页数：10

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