REGRESSION OF METASTATIC RENAL-CELL CARCINOMA AFTER CYTOREDUCTIVE NEPHRECTOMY

被引:105
作者
MARCUS, SG [1 ]
CHOYKE, PL [1 ]
REITER, R [1 ]
JAFFE, GS [1 ]
ALEXANDER, RB [1 ]
LINEHAN, WM [1 ]
ROSENBERG, SA [1 ]
WALTHER, MM [1 ]
机构
[1] NCI,DEPT DIAGNOST RADIOL,BETHESDA,MD 20892
关键词
KIDNEY; NEPHRECTOMY; CARCINOMA; RENAL CELL; NEOPLASM METASTASIS; NEOPLASM REGRESSION; SPONTANEOUS;
D O I
10.1016/S0022-5347(17)35514-3
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Fewer than 1% of patients with renal cell carcinoma are reported to experience spontaneous regression of metastatic lesions after nephrectomy. We report on 4 of 91 patients (4.4%) with metastatic renal cell carcinoma who had spontaneous regression of all metastatic lesions after cytoreductive nephrectomy. These patients were carefully selected before surgery for the ability to receive high dose interleukin-2. One patient had recurrence at 2 months, 1 had recurrence at 11 months, and 2 had no evidence of disease at 3 and 4.5 years.
引用
收藏
页码:463 / 466
页数:4
相关论文
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