DOES OXIMETRY CONTRIBUTE TO THE DETECTION OF APNEIC EVENTS - MATHEMATICAL-PROCESSING OF THE SAO2 SIGNAL

被引:48
作者
PEPIN, JL
LEVY, P
LEPAULLE, B
BRAMBILLA, C
GUILLEMINAULT, C
机构
[1] UNIV HOSP GRENOBLE,DEPT PNEUMOL,GRENOBLE,FRANCE
[2] UNIV HOSP GRENOBLE,SLEEP LAB,GRENOBLE,FRANCE
[3] STANFORD UNIV,MED CTR,SCH MED,CTR SLEEP DISORDERS,STANFORD,CA 94305
关键词
D O I
10.1378/chest.99.5.1151
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The purpose of this study was to assess the ability of continuous nocturnal oximetry to detect sleep apnea syndrome (SAS) and to recognize nonapneic oxyhemoglobin desaturations. Oxygen saturation oscillations, related to successive apneas in SAS or to apneic episodes in COPD or restrictive patients, were quantified using a new index: [GRAPHICS] Twenty-six patients (15 SAS, 8 COPD, and 3 restrictive patients) were included in a prospective study comparing nocturnal oximetry and polysomnography over 34 nights. In apneic patients, we found a strong correlation (r2 = 0.73, p < 0.01) between time spent in apnea and the delta index. In COPD, the number of apneas was also correlated to the DELTA index (r2 = 0.92, p < 0.01). A lower threshold for delta of 1.5 is accurate enough to detect apneas if initial SaO2 is < 93 percent. If initial SaO2 is greater than 93 percent, the delta threshold should be 0.8 (sensitivity 95 percent). Such a method could contribute to the accurate selection of patients for polysomnography.
引用
收藏
页码:1151 / 1157
页数:7
相关论文
共 20 条
[11]   PRIMER ON CERTAIN ELEMENTS OF MEDICAL DECISION-MAKING [J].
MCNEIL, BJ ;
KEELER, E ;
ADELSTEIN, SJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1975, 293 (05) :211-215
[12]  
Quanjer P.H., 1983, B EUR PHYSIOPATHO S5, V19, P11
[13]  
Rechtschaffen A, 1968, NIH PUBLICATION, V204
[14]  
SMITH P L, 1984, American Review of Respiratory Disease, V129, pA56
[15]   WEIGHT-LOSS IN MILDLY TO MODERATELY OBESE PATIENTS WITH OBSTRUCTIVE SLEEP-APNEA [J].
SMITH, PL ;
GOLD, AR ;
MEYERS, DA ;
HAPONIK, EF ;
BLEECKER, ER .
ANNALS OF INTERNAL MEDICINE, 1985, 103 (06) :850-855
[16]   OXYGEN-SATURATION DURING BREATH-HOLDING AND DURING APNEAS IN SLEEP [J].
STROHL, KP ;
ALTOSE, MD .
CHEST, 1984, 85 (02) :181-186
[17]  
SULLIVAN CE, 1981, LANCET, V1, P862
[18]   EVALUATION OF THE OHMEDA 3700 PULSE OXIMETER [J].
WARLEY, ARH ;
MITCHELL, JH ;
STRADLING, JR .
THORAX, 1987, 42 (11) :892-896
[19]   DYNAMIC INVIVO RESPONSE CHARACTERISTICS OF 3 OXIMETERS - HEWLETT-PACKARD 47201A, BIOX-III, AND NELLCOR N-100 [J].
WEST, P ;
GEORGE, CF ;
KRYGER, MH .
SLEEP, 1987, 10 (03) :263-271
[20]  
1989, AM REV RESPIR DIS, V139, P559