NUCLEOTIDE-SEQUENCE OF AMPICILLIN RESISTANCE GENE OF ESCHERICHIA-COLI PLASMID PBR322

被引：789

作者：

SUTCLIFFE, JG ^{[1
]}

机构：

[1] HARVARD UNIV,BIOL LABS,CAMBRIDGE,MA 02138

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1978年 / 75卷 / 08期

关键词：

D O I：

10.1073/pnas.75.8.3737

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The nucleotide sequence of the ampicillin resistance gene of pBR322, an E. coli plasmid that encodes a penicillin β-lactamase, was determined. This gene codes for a protein of 286 amino acid residues. The first 23 amino acids presumably form a signal for secretion, because they do not appear in the mature enzyme, whose partial amino acid sequence has been determined independently.

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页码：3737 / 3741

页数：5

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