AGE-DIFFERENCES AND STRESS-ULCER IN THE RAT

被引：18

作者：

PARE, WP

VINCENT, GP

ISOM, KE

机构：

[1] Pavlovian Research Laboratory, Veterans Administration Medical Center, Perry Point, MD

来源：

EXPERIMENTAL AGING RESEARCH | 1979年 / 5卷 / 01期

关键词：

D O I：

10.1080/03610737908257186

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Rats 2-, 7- and 12- mo. old were exposed to supine body restraint plus cold (5°C) for 3 hr. The mean cumulative length of lesions for the 2-, 7-, and 12 mo. old rats was 22.0, 43.0 and 16.0 mm. respectively. The same experimental design was used in a second study, but the pylorus was ligated prior to restraint. Total acid output/hr. was 134.6, 178.2, and 64.7 μEq/60 min. respectively for the three age groups. Older rats were not more susceptible to stress-ulcer and gastric acid was not significantly related to degree of ulceration. © 1979 Taylor & Francis Group, LLC.

引用

页码：31 / 42

页数：12

共 24 条

[11]

KIMMEL DC, 1974, ADULTHOOD AGING INTD

[12]

Kohn RR, 1971, PRINCIPLES MAMMALIAN

[13] AGING RESEARCH .2. PACEMAKERS FOR AGING [J].

MARX, J .

SCIENCE, 1974, 186 (4170) :1196-1197

[14] FOOD DEPRIVATION, SHOCK STRESS AND STOMACH LESIONS IN RAT [J].

PARE, WP ;

TEMPLE, LJ .

PHYSIOLOGY & BEHAVIOR, 1973, 11 (03) :371-375

[15] CONFLICT DURATION, FEEDING SCHEDULE, AND STRAIN DIFFERENCES IN CONFLICT-INDUCED GASTRIC-ULCERS [J].

PARE, WP .

PHYSIOLOGY & BEHAVIOR, 1972, 8 (02) :165-+

[16] GASTRIC-SECRETION AND ACTIVITY-STRESS LESIONS IN RAT [J].

PARE, WP .

JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY, 1977, 91 (04) :778-783

[17]

RHODES J, 1972, GASTROENTEROLOGY, V63, P171

[18] AGE WEIGHT AND SOCIAL EFFECTS ON ULCERATION RATE IN RATS [J].

SAWREY, JM ;

SAWREY, WL .

JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY, 1966, 61 (03) :464-&

[19] BILE AND STRESS ULCER IN RAT [J].

SCHUMPELICK, V .

LANGENBECKS ARCHIV FUR CHIRURGIE, 1975, 338 (04) :265-274

[20] ETIOLOGY OF PEPTIC ULCER [J].

SHAY, H .

AMERICAN JOURNAL OF DIGESTIVE DISEASES, 1961, 6 (01) :29-+

← 1 2 3 →