EFFICACY OF 2'-NOR-CYCLICGMP IN TREATMENT OF EXPERIMENTAL HERPESVIRUS INFECTIONS

被引：16

作者：

FIELD, AK ^{[1
]}

DAVIES, MEM ^{[1
]}

DEWITT, CM ^{[1
]}

PERRY, HC ^{[1
]}

SCHOFIELD, TL ^{[1
]}

KARKAS, JD ^{[1
]}

GERMERSHAUSEN, J ^{[1
]}

WAGNER, AF ^{[1
]}

CANTONE, CL ^{[1
]}

MACCOSS, M ^{[1
]}

TOLMAN, RL ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS, RAHWAY, NJ 07065 USA

来源：

ANTIVIRAL RESEARCH | 1986年 / 6卷 / 06期

关键词：

D O I：

10.1016/0166-3542(86)90015-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：329 / 341

页数：13

共 22 条

[1] SYNTHESIS AND ANTIHERPETIC ACTIVITY OF (S)-9-[2,3-DIHYDROXY-1-PROPOXY)METHYL]GUANINE, (R)-9-[2,3-DIHYDROXY-1-PROPOXY)METHYL]GUANINE, AND (+/-)-9-[(2,3-DIHYDROXY-1-PROPOXY)METHYL]GUANINE, LINEAR ISOMERS OF 2'-NOR-2'-DEOXYGUANOSINE
ASHTON, WT
CANNING, LF
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DAVIES, MEM
DEWITT, CM
PERRY, HC
FIELD, AK
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (07) : 926 - 933
[2] ASHTON WT, 1983, BIOCHEM BIOPH RES CO, V108, P1718
[3] BLISS CJ, 1967, STAT BIOL, P63
[4] UNIQUE SPECTRUM OF ACTIVITY OF 9-[(1,3-DIHYDROXY-2-PROPOXY)METHYL]-GUANINE AGAINST HERPESVIRUSES INVITRO AND ITS MODE OF ACTION AGAINST HERPES-SIMPLEX VIRUS TYPE-1
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (09): : 2767 - 2770
[5] Coen DM, 1980, ANIMAL VIRUS GENETIC, P581
[6] INCUBATION OF SWAB MATERIALS WITH HERPES-SIMPLEX VIRUS
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[J]. JOURNAL OF INFECTIOUS DISEASES, 1980, 141 (04) : 531 - 531
[7] DAVIES MEM, 1984, ANTIMICROB AGENTS CH, V25, P238, DOI 10.1128/AAC.25.2.238
[8] SELECTIVITY OF ACTION OF AN ANTI-HERPETIC AGENT, 9-(2-HYDROXYETHOXYMETHYL)GUANINE
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) : 5716 - 5720
[9] ANTIGENIC RELATIONSHIPS AMONG SEVERAL SIMIAN VARICELLA-LIKE VIRUSES AND VARICELLA-ZOSTER VIRUS
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SCHMIDT, NJ
[J]. INFECTION AND IMMUNITY, 1977, 15 (03) : 807 - 812
[10] 9-([2-HYDROXY-1-(HYDROXYMETHYL)ETHOXY]METHYL)GUANINE - A SELECTIVE INHIBITOR OF HERPES GROUP VIRUS-REPLICATION
FIELD, AK
DAVIES, ME
DEWITT, C
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LIOU, R
GERMERSHAUSEN, J
KARKAS, JD
ASHTON, WT
JOHNSTON, DBR
TOLMAN, RL
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (13): : 4139 - 4143

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