POLYGLUCOSAN BODIES IN SURAL NERVE BIOPSIES

被引:23
作者
BUSARD, HLSM
GABREELSFESTEN, AAWM
VANTHOF, MA
RENIER, WO
GABREELS, FJM
机构
[1] UNIV HOSP NIJMEGEN,INST NEUROL,POB 9101,6500 HB NIJMEGEN,NETHERLANDS
[2] UNIV HOSP NIJMEGEN,DEPT STAT CONSULTAT,6500 HB NIJMEGEN,NETHERLANDS
关键词
Ageing; Lafora's disease; Polyglucosan bodies; Sural nerve biopsy;
D O I
10.1007/BF00294618
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The presence of polyglucosan bodies in sural nerves collected over a 16-year period was studied in relation to age, sex, presence of polyneuropathy, and concomitant presence of central nervous system disorder. Polyglucosan bodies have been seen in only one patient without a polyneuropathy. This patient was suffering from Lafora's disease. In all other sural nerves positive for polyglucosan bodies a polyneuropathy was present. Within this group the prevalence of polyglucosan bodies was positively correlated with age, and if a central nervous system disorder was associated, this prevalence was more distinct. With semiquantitative measurements of the surface of polyglucosan bodies a significant correlation was found between age and percentage of large bodies. © 1990 Springer-Verlag.
引用
收藏
页码:554 / 557
页数:4
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