A NONPEPTIDIC ION-CHANNEL WITH K+ SELECTIVITY

被引：150

作者：

TANAKA, Y

KOBUKE, Y

SOKABE, M

机构：

[1] SHIZUOKA UNIV,FAC ENGN,DEPT MAT SCI,HAMAMATSU,SHIZUOKA 432,JAPAN

[2] NAGOYA UNIV,NAGOYA,AICHI,JAPAN

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 06期

关键词：

ION CHANNELS; MEMBRANE MODELS; RESORCINOL;

D O I：

10.1002/anie.199506931

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The resorcinol–octadecanal cyclotetramer 1 forms an ion channel in planar lipid bilayers. A stable conductance level is observed with well‐defined transitions between open and closed states. The channel discriminates K+ from Na+ ions as well as cations from anions (for example, K+ from Cl−), as indicated by permeability ratios of 3 and 20, respectively. Rb+ ions block the K+ ion current. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

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页码：693 / 694

页数：2

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