TREATMENT OF VAGINAL CANDIDIASIS WITH KETOCONAZOLE, A NEW, ORALLY ACTIVE, ANTI-MYCOTIC

被引：48

作者：

BISSCHOP, MPJM

MERKUS, JMWM

SCHEYGROND, H

VANCUTSEM, J

VANDEKUY, A

机构：

[1] MARIA HOSP,DEPT CLIN PHARM,TILBURG,NETHERLANDS

[2] JANSSEN PHARM,DEPT CLIN RES,B-2340 BEERSE,BELGIUM

[3] JANSSEN PHARM,DEPT CHEMOTHERAPY,B-2340 BEERSE,BELGIUM

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1979年 / 9卷 / 04期

关键词：

Candida albicans; ketoconazole; vulvovaginitis;

D O I：

10.1016/0028-2243(79)90065-0

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The efficacy of a new, orally active antimycotic, ketoconazole, in the treatment of vaginal candidiasis was studied at different doses involving 63 patients. All patients had subjective complaints and were mycologically positive. There was no significant difference in the cure rates of the different doses. The oral treatment was successful in 55 out of 63 patients (87.3%). No correlation was found between the relapse rate of vaginal candidiasis and the dose regimen. There were no serious side-effects, and no significant changes were reported in hematological and biochemical parameters. © 1979.

引用

页码：253 / 259

页数：7

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