AN EFFICIENT SYNTHESIS OF DIETHYL 1-AMINOALKYLPHOSPHONATE HYDROCHLORIDES VIA THE INTERMEDIATE DIETHYL 1-AZIDOALKYLPHOSPHONATES

被引：38

作者：

GAJDA, T

MATUSIAK, M

机构：

[1] Institute of Oragnic Chemistry, Technical University, Zwirki 36

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 15期

关键词：

D O I：

10.1080/00397919208019072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compounds 4 have been obtained in high yields in a one-step sequence by the Mitsunobu reaction of diethyl 1-hydroxyalkylphosphonates 1 with hydrazoic acid, and subsequence treatment of the intermediate azides 2 with triphenylphosphine, followed by hydrolysis of the iminophosphoranes 3 with water.

引用

页码：2193 / 2203

页数：11

共 30 条

[21] KOWALIK J, 1981, SYNTHESIS-STUTTGART, P57
[22] Kukhar V. P., 1987, RUSS CHEM REV+, V56, P859
[23] KUKHAR VP, 1987, USP KHIM+, V56, P1504
[24] ORGANIC PHOSPHORUS-COMPOUNDS 91.1 SYNTHESIS AND PROPERTIES OF 1-AMINO-2-ARYLETHYLPHOSPHONIC AND ARYLETHYLPHOSPHINIC ACIDS AS WELL AS ARYLETHYLPHOSPHINE OXIDES
MAIER, L
[J]. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1990, 53 (1-4): : 43 - 67
[25] MAIER L, 1991, PHOSPHORUS SULFUR SI, V57, P67
[26] THE USE OF DIETHYL AZODICARBOXYLATE AND TRIPHENYLPHOSPHINE IN SYNTHESIS AND TRANSFORMATION OF NATURAL-PRODUCTS
MITSUNOBU, O
[J]. SYNTHESIS-STUTTGART, 1981, (01): : 1 - 28
[27] RABJOHN N, 1955, ORG SYNTH, V3, P375
[28] RACHON J, 1975, ROCZ CHEM, V49, P397
[29] SOROKA M, 1988, SYNTHESIS-STUTTGART, P370
[30] WOLF H, 1947, ORG REACTIONS, V3, P327

← 1 2 3 →