LYCORINE ALKALOIDS FROM HYMENOCALLIS-LITTORALIS

被引：72

作者：

LIN, LZ

HU, SF

CHAI, HB

PENGSUPARP, T

PEZZUTO, JM

CORDELL, GA

RUANGRUNGSI, N

机构：

[1] UNIV ILLINOIS,COLL PHARM,DEPT MED CHEM & PHARMACOGNOSY,PROGRAM COLLABORAT RES PHARMACEUT SCI,CHICAGO,IL 60612

[2] CHULALONGKORN UNIV,FAC PHARMACEUT SCI,DEPT PHARMACOGNOSY,BANGKOK 10330,THAILAND

来源：

PHYTOCHEMISTRY | 1995年 / 40卷 / 04期

关键词：

HYMENOCALLIS LITTORALIS; AMARYLLIDACEAE; LYCORINE ALKALOIDS; LITTORALINE; STRUCTURE DETERMINATION; BIOLOGICAL EVALUATION;

D O I：

10.1016/0031-9422(95)00372-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

From Hymenocallis littoralis, one new alkaloid, named littoraline, together with 13 known lycorine alkaloids and one lignan, were isolated. The structure and NMR assignments of this new alkaloid were determined by 1D and 2D NMR techniques. Littoraline showed inhibitory activity of HIV reverse transcriptase, and lycorine and haemanthamine showed potent in vitro cytotoxicity.

引用

页码：1295 / 1298

页数：4

共 18 条

[1] DELTA-POLARIZATION TRANSFER VIA LONG-RANGE COUPLING AS A SIMPLE ONE-DIMENSIONAL NMR TECHNIQUE FOR H-1-C-13 CORRELATION - APPLICATION TO THE DEFINITIVE ASSIGNMENT OF THE SYN AND ANTI C-13 DELTA-RESONANCES OF 2-SUBSTITUTED ADAMANTANES [J].