DETERMINATION OF CATECHOLAMINES AND URIC-ACID IN BIOLOGICAL-FLUIDS WITHOUT PRETREATMENT, USING CHEMICALLY AMPLIFIED BIOSENSORS

被引：23

作者：

HASEBE, Y

HIRANO, T

UCHIYAMA, S

机构：

[1] Department of Environmental Engineering, Saitama Institute of Technology, Okabe, Saitama, 369-02

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 1995年 / 24卷 / 1-3期

关键词：

CATECHOLAMINES; BIOSENSORS; CHEMICAL AMPLIFICATION; URIC ACID;

D O I：

10.1016/0925-4005(95)85020-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Chemically amplified biosensors based on substrate recycling using oxidase and reducing agents have been applied to the convenient detection of catecholamines and uric acid in biological fluids. These methods are based on the highly sensitive detection of trace amounts of analytes (10(-8) M level) in highly diluted (1000-10000 fold) body samples, in which the interfering species are also diluted to negligible concentration level for an amperometric measurement. The concentration of uric acid obtained by the chemically amplified uric acid sensor is in fairly good agreement with that obtained by conventional spectrophotometry.

引用

页码：94 / 97

页数：4

共 7 条

[1] HIGHLY AMPLIFIED SPECTROPHOTOMETRY OF POLYPHENOLS BASED ON A CYCLIC REACTION BETWEEN POLYPHENOLS AND O-QUINONE COMPOUNDS USING TYROSINASE AND L-ASCORBIC-ACID [J].