IMMUNOAFFINITY CHROMATOGRAPHY COMBINED WITH GAS-CHROMATOGRAPHY NEGATIVE-ION CHEMICAL IONIZATION MASS-SPECTROMETRY FOR THE CONFIRMATION OF FLUMETHASONE ABUSE IN THE EQUINE

被引：20

作者：

STANLEY, SMR ^{[1
]}

WILHELMI, BS ^{[1
]}

RODGERS, JP ^{[1
]}

BERTSCHINGER, H ^{[1
]}

机构：

[1] UNIV PRETORIA,FAC VET SCI,DEPT GENESIOL,ONDERSTEPOORT 0110,SOUTH AFRICA

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1993年 / 614卷 / 01期

关键词：

D O I：

10.1016/0378-4347(93)80225-S

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Immunoaffinity chromatography using a synthesised immunosorbent was used to extract tritiated dexamethasone (with dexamethasone carrier) from equine urine at a recovery of 81.7 +/- 8.4% (mean +/- S.D.). A method utilising this procedure coupled to cool on-column injection gas chromatography-negative ion chemical ionisation mass spectrometry is also described for the confirmation of low levels of flumethasone in equine urine samples.

引用

页码：77 / 86

页数：10

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