HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF CIS-TRANS ISOMERS OF PROLINE-CONTAINING DIPEPTIDES .3. COMPARATIVE-STUDIES WITH DIFFERENT STATIONARY PHASES

被引：23

作者：

WUTTE, A

GUBITZ, G

FRIEBE, S

KRAUSS, GJ

机构：

[1] UNIV HALLE WITTENBERG,DEPT BIOCHEM & BIOTECHNOL,D-06120 HALLE,GERMANY

[2] KARL FRANZENS UNIV GRAZ,INST PHARMACEUT CHEM,A-8010 GRAZ,AUSTRIA

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 677卷 / 01期

关键词：

D O I：

10.1016/0021-9673(94)80558-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Different stationary phases were compared for their capacity to separate cis-trans isomers of proline-containing dipeptides for equilibrium and isomerization studies. Both reversed-phase chromatography on an RP-18 or a graphitized carbon phase (Hypercarb S) and ligand-exchange chromatography on an L-proline-Cu(II) phase can be used effectively to separate the cls-trans isomers.

引用

收藏

页码：186 / 191

页数：6

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