SYNTHESIS OF NANOPARTICLES FOR BRAIN-CELL LABELING INVIVO

被引：10

作者：

PAULKE, BR

HARTIG, W

BRUCKNER, G

机构：

[1] INST POLYMER CHEM, O-1530 TELTOW, GERMANY

[2] UNIV LEIPZIG, PAUL FLECHSIG INST BRAIN RES, O-7010 LEIPZIG, GERMANY

来源：

ACTA POLYMERICA | 1992年 / 43卷 / 05期

关键词：

D O I：

10.1002/actp.1992.010430510

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Different types of latices were synthesized by emulsion copolymerization that differ in particle size, polymer hydrophilicity and surface coverage with functional groups. All of these particles were equipped with intensive fluorescence by inclusion polymerization, covalent bonding during particle formation and growth or surface modification of pre-fabricated latices, respectively. Concentrated particle suspensions were injected into the brain tissue of mice. The filling of glial cells by phagocytosis and the retrograde labelling of neurons with two kinds of beads could be shown in brain sections.

引用

页码：288 / 291

页数：4

共 27 条

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Bangs LB, 1984, UNIFORM LATEX PARTIC

[2] THE PREPARATION OF SMALL POLYSTYRENE LATEX-PARTICLES [J].