INNERVATION OF THE PANCREAS BY SUBSTANCE-P, ENKEPHALIN, VASOACTIVE INTESTINAL POLYPEPTIDE AND GASTRIN-CCK IMMUNOREACTIVE NERVES

被引:146
作者
LARSSON, LI
机构
关键词
D O I
10.1177/27.9.479572
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Immunocytochemical studies have shown that many peptides which profoundly affect the endocrine and exocrine functions of the pancreas are localized to neurons. In the cat, such peptidergic nerves appear to innervate ganglia, islets and blood vessels of the pancreas, whereas their contributions to exocrine cells are minor. Our studies suggest that pancreatic ganglia represent one major site of action of the peptides and that, in addition, nerves containing the vasoactive intestinal polypeptide and gastrin/CCK-related peptides profoundly affect pancreatic blood flow and insulin secretion, respectively.
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页码:1283 / 1284
页数:2
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