GENETIC-LINKAGE OF C3H-HEJ AND BALB-C ENDOGENOUS ECOTROPIC C-TYPE VIRUSES TO PHOSPHOGLUCOMUTASE-1 ON CHROMOSOME-5

被引:52
作者
IHLE, JN
JOSEPH, DR
DOMOTOR, JJ
机构
[1] Cancer Biology Program, Frederick Cancer Research Center, Frederick
关键词
D O I
10.1126/science.219476
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The genetic linkage of the endogenous C3H/HeJ C-type ecotropic virus to phosphoglucomutase-1 (0.28, recombinant fraction) on chromosome 5 was established by means of serological assays of backcrossed mice. With a combination of serological techniques and DNA-DNA hybridization the BALBIc endogenous ecotropic virus was shown to be either closely linked or allelic with the C3H/HeJ locus. Copyright © 1979 AAAS.
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页码:71 / 73
页数:3
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