COMPLEMENT ACTIVATION DURING BYPASS IN ACQUIRED C1 ESTERASE INHIBITOR DEFICIENCY

被引：24

作者：

BONSER, RS

DAVE, J

MORGAN, J

MORGAN, C

DAVIES, E

TAYLOR, P

GAYA, H

JOHN, L

PANETH, M

VERGANI, D

机构：

[1] BROMPTON HOSP,LONDON SW3 6HP,ENGLAND

[2] UNIV LONDON KINGS COLL HOSP,LONDON SE5 8RX,ENGLAND

来源：

ANNALS OF THORACIC SURGERY | 1991年 / 52卷 / 03期

关键词：

D O I：

10.1016/0003-4975(91)90921-C

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Serial complement estimations during cardiopulmonary bypass are reported in a patient with acquird C1 esterase inhibitor deficiency. Although the extent of classic and alternative pathway activation appeared appropriate, exaggerated common pathway activation with massive increase in the C3d:C3 ratio occurred. A fatal hemostatic disorder, pulmonary edema, and circulatory collapse ensued despite prophylaxis and therapy.

引用

收藏

页码：541 / 543

页数：3

相关论文

共 10 条

[1] COMPLEMENT ACTIVATION BEFORE, DURING AND AFTER CARDIOPULMONARY BYPASS [J].

BONSER, RS ;

DAVE, JR ;

JOHN, L ;

GADEMSETTY, MK ;

CARTER, PG ;

DAVIES, E ;

TAYLOR, P ;

GAYA, H ;

LENNOX, SC ;

VERGANI, D .

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 1990, 4 (06) :291-296

[2]

BONSER RS, IN PRESS TECHNIQUES

[3] EPSILON AMINOCAPROIC ACID THERAPY OF HEREDITARY ANGIONEUROTIC EDEMA - DOUBLE-BLIND STUDY [J].

FRANK, MM ;

SERGENT, JS ;

KANE, MA ;

ALLING, DW .

NEW ENGLAND JOURNAL OF MEDICINE, 1972, 286 (15) :808-&

[4] REPLACEMENT THERAPY IN HEREDITARY ANGIOEDEMA - SUCCESSFUL TREATMENT OF ACUTE EPISODES OF ANGIOEDEMA WITH PARTLY PURIFIED C1-INHIBITOR [J].

GADEK, JE ;

HOSEA, SW ;

GELFAND, JA ;

SANTAELLA, M ;

WICKERHAUSER, M ;

TRIANTAPHYLLOPOULOS, DC ;

FRANK, MM .

NEW ENGLAND JOURNAL OF MEDICINE, 1980, 302 (10) :542-546

[5] ACQUIRED C1 ESTERASE INHIBITOR DEFICIENCY AND ANGIOEDEMA - REVIEW [J].

GELFAND, JA ;

BOSS, GR ;

CONLEY, CL ;

REINHART, R ;

FRANK, MM .

MEDICINE, 1979, 58 (04) :321-328

[6] TREATMENT OF ACQUIRED C-1(-)-INHIBITOR DEFICIENCY WITH DANAZOL [J].

HAUPTMANN, G ;

OBERLING, F ;

MAYER, G ;

MAYER, S ;

LANG, JM .

ANNALS OF INTERNAL MEDICINE, 1977, 87 (05) :577-578

[7]

JAFFE CS, 1975, J ALLERGY CLIN IMMUN, V155, P386

[8]

METZGER WJ, 1984, ANN ALLERGY, V52, P285

[9]

SHEFFER AL, 1976, NEW ENGL J MED, V295, P1444

[10] HEREDITARY ANGIONEUROTIC-EDEMA - REPORT OF A CASE UNDERGOING OPEN-HEART-SURGERY - A CASE-REPORT [J].

UMEBAYASHI, Y ;

MORISHITA, Y ;

ARIKAWA, K ;

SAKAMOTO, H ;

TAIRA, A ;

SANO, Y .

VASCULAR SURGERY, 1987, 21 (02) :138-141