EXERCISE, MUSCLE DAMAGE AND FATIGUE

被引：119

作者：

APPELL, HJ

SOARES, JMC

DUARTE, JAR

机构：

[1] Institute for Experimental Morphology, German Sports University, Cologne, D-5000

[2] Department of Sport Biology, University of Porto

来源：

SPORTS MEDICINE | 1992年 / 13卷 / 02期

关键词：

D O I：

10.2165/00007256-199213020-00006

中图分类号：

G8 [体育];

学科分类号：

04 ; 0403 ;

摘要：

Fatigue as a functional sign and muscle damage as a structural sign can be observed after prolonged exercise like marathon running or after strenuous exercise, especially with the involvement of eccentric contractions. For fatigue due to prolonged exercise, hypoxic conditions and the formation of free oxygen radicals seem to be of aetiological importance, resulting in an elevated lysosomal activity. Eccentric exercise of high intensity rather results in a mechanical stress to the fibres. Although these different mechanisms can be discerned experimentally, both result in similar impairments of muscle function. A good training status may attenuate the clinical signs of fatigue and muscle damage. The symptoms and events occurring during delayed onset of muscle soreness (DOMS) can be explained by a cascade of events following structural damage to muscle proteins.

引用

页码：108 / 115

页数：8

共 43 条

[21] Kuipers H., Drukker J., Frederick P.M., Geurten P., von Kranenburg G., Muscle degeneration after exercise in rats, International Journal of Sports Medicine, 4, pp. 45-51, (1983)
[22] Newham D.J., Jones D.A., Clarkson P.M., Repeated high-force eccentric exercise: effects on muscle pain and damage, Journal of Applied Physiology, 63, pp. 1381-1386, (1987)
[23] Newham D.J., McPhail G., Mills K.B., Edwards R.H.T., Ultrastructural changes after concentric and eccentric contractions of human muscle, Journal of Neurological Science, 61, pp. 109-122, (1983)
[24] O'Reilly K.P., Warhol M.J., Fielding R.A., Frontera W.R., Meredith C.N., Et al., Eccentric exercise-induced muscle damage impairs muscle glycogen repletion, Journal of Applied Physiology, 63, pp. 252-256, (1987)
[25] Payne C.M., Stern L.Z., Curless R.G., Hannapel L.K., Ultrastructural fiber typing in normal and diseased human muscle, Journal of Neurological Science, 25, pp. 88-108, (1975)
[26] Rall J.A., Energetic aspects of skeletal muscle contraction: implication of fiber types, Exercise and Sports Science Reviews, 13, pp. 33-74, (1985)
[27] Salminen A., Vihko V., Acid proteolytic capacity in mouse cardiac and skeletal muscles after prolonged submaximal exercise, Pflügers Archiv, 389, pp. 17-20, (1980)
[28] Salminen A., Hongisto K., Vihko V., Lysosomal changes related to exercise injuries and training-induced protection in mouse skeletal muscle, Acta Physiologica Scandinavica, 120, pp. 15-20, (1984)
[29] Salminen A., Vihko V., Endurance training reduces the susceptibility of mouse skeletal muscle to lipid peroxidation in vitro, Acta Physiologica Scandinavica, 117, pp. 109-113, (1983)
[30] Salminen A., Vihko V., Autophagic response to strenuous exercise in mouse skeletal muscle fibers, Virchows Archiv (Cell Pathology), 45, pp. 97-106, (1984)

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