RELOCALIZATION OF ACTSK-1 TO MOUSE CHROMOSOME-8, A NEW REGION OF HOMOLOGY WITH HUMAN CHROMOSOME-1

被引：9

作者：

ALONSO, S ^{[1
]}

MONTAGUTELLI, X ^{[1
]}

SIMONCHAZOTTES, D ^{[1
]}

GUENET, JL ^{[1
]}

BUCKINGHAM, M ^{[1
]}

机构：

[1] INST PASTEUR,UNITE GENET MAMMIFERES,URA 361,F-75724 PARIS 15,FRANCE

来源：

MAMMALIAN GENOME | 1993年 / 4卷 / 01期

关键词：

D O I：

10.1007/BF00364657

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We present here the genetic mapping of the alpha-skeletal actin locus (Actsk-1) on mouse Chromosome (Chr) 8, on the basis of the PCR analysis of a microsatellite in an interspecific backcross. Linkage and genetic distances were established for four loci by analysis of 192 (or 222) melotic events and indicated the following gene order: (centromere)-Es-1-11.7 cM-Tat-8.3 cM-Actsk-1-0.5 cM-Aprt. Mapping of ACTSK to human Chr 1 and of TAT and APRT to human Chr 16 demonstrates the existence of a new short region of homology between mouse Chr 8 and human Chr 1. Intermingling on this scale between human and mouse chromosomal homologies that occurred during evolution creates disorders in comparative linkage studies.

引用

页码：15 / 20

页数：6

共 33 条

[1] LINKAGE OF AGT AND ACTSK-1 TO DISTAL MOUSE CHROMOSOME-8 LOCI - A NEW CONSERVED LINKAGE
ABONIA, JP
ABEL, KJ
EDDY, RL
ELLIOTT, RW
CHAPMAN, VM
SHOWS, TB
GROSS, KW
[J]. MAMMALIAN GENOME, 1993, 4 (01) : 25 - 32
[2] GENETIC-ANALYSIS OF THE INTERACTION BETWEEN CARDIAC AND SKELETAL ACTIN GENE-EXPRESSION IN STRIATED-MUSCLE OF THE MOUSE
ALONSO, S
GARNER, I
VANDEKERCKHOVE, J
BUCKINGHAM, M
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1990, 211 (04) : 727 - 738
[3] THE HUMAN TYROSINE AMINOTRANSFERASE GENE MAPPED TO THE LONG ARM OF CHROMOSOME-16 (REGION 16Q22-]Q24) BY SOMATIC-CELL HYBRID ANALYSIS AND INSITU HYBRIDIZATION
BARTON, DE
YANGFENG, TL
FRANCKE, U
[J]. HUMAN GENETICS, 1986, 72 (03) : 221 - 224
[4] Ceci J D, 1991, Mamm Genome, V1 Spec No, pS112, DOI 10.1007/BF00656489
[5] THE ANGIOTENSINOGEN GENE IS LOCATED ON MOUSE CHROMOSOME-8
CLOUSTON, WM
FOURNIER, REK
RICHARDS, RI
[J]. FEBS LETTERS, 1989, 255 (02) : 419 - 422
[6] THE CARDIAC ACTIN LOCUS (ACTC-1) IS NOT ON MOUSE CHROMOSOME-17 BUT IS LINKED TO BETA-2-MICROGLOBULIN ON CHROMOSOME-2
CROSBY, JL
PHILLIPS, SJ
NADEAU, JH
[J]. GENOMICS, 1989, 5 (01) : 19 - 23
[7] THE GENES-CODING FOR THE MUSCLE CONTRACTILE PROTEINS, MYOSIN HEAVY-CHAIN, MYOSIN LIGHT CHAIN-2, AND SKELETAL-MUSCLE ACTIN ARE LOCATED ON THREE DIFFERENT MOUSE CHROMOSOMES
CZOSNEK, H
NUDEL, U
SHANI, M
BARKER, PE
PRAVTCHEVA, DD
RUDDLE, FH
YAFFE, D
[J]. EMBO JOURNAL, 1982, 1 (11) : 1299 - 1305
[8] THE GENES-CODING FOR THE CARDIAC-MUSCLE ACTIN, THE SKELETAL-MUSCLE ACTIN AND THE CYTOPLASMIC BETA-ACTIN ARE LOCATED ON 3 DIFFERENT MOUSE CHROMOSOMES
CZOSNEK, H
NUDEL, U
MAYER, Y
BARKER, PE
PRAVTCHEVA, DD
RUDDLE, FH
YAFFE, D
[J]. EMBO JOURNAL, 1983, 2 (11) : 1977 - 1979
[9] CZOSNEK H, 1982, EMBO J, V2, P1977
[10] NUCLEOTIDE-SEQUENCE AND ORGANIZATION OF THE MOUSE ADENINE PHOSPHORIBOSYLTRANSFERASE GENE - PRESENCE OF A CODING REGION COMMON TO ANIMAL AND BACTERIAL PHOSPHORIBOSYLTRANSFERASES THAT HAS A VARIABLE INTRON EXON ARRANGEMENT
DUSH, MK
SIKELA, JM
KHAN, SA
TISCHFIELD, JA
STAMBROOK, PJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (09) : 2731 - 2735

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