SPECIES VARIATION AND STEREOSELECTIVITY IN THE METABOLISM OF NICOTINE ENANTIOMERS

被引：31

作者：

NWOSU, CG

CROOKS, PA

机构：

[1] UNIV KENTUCKY,COLL PHARM,LEXINGTON,KY 40536

[2] UNIV KENTUCKY,GRAD CTR TOXICOL,LEXINGTON,KY 40536

来源：

XENOBIOTICA | 1988年 / 18卷 / 12期

关键词：

D O I：

10.3109/00498258809042260

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：1361 / 1372

页数：12

共 13 条

[1]

BECKETT AH, 1971, J PHARM PHARM S, V23, P62

[2] STEREOSPECIFIC INVITRO N-METHYLATION OF NICOTINE IN GUINEA-PIG TISSUES BY AN S-ADENOSYLMETHIONINE-DEPENDENT N-METHYLTRANSFERASE [J].

CUNDY, KC ;

GODIN, CS ;

CROOKS, PA .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (02) :281-284

[3] REMARKABLE SUBSTRATE-INHIBITOR PROPERTIES OF NICOTINE ENANTIOMERS TOWARDS A GUINEA-PIG LUNG AROMATIC AZAHETEROCYCLE N-METHYLTRANSFERASE [J].

CUNDY, KC ;

CROOKS, PA ;

GODIN, CS .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 128 (01) :312-316

[4]

CUNDY KC, 1985, DRUG METAB DISPOS, V13, P175

[5] BIOTRANSFORMATION OF PRIMARY NICOTINE METABOLITES .2. METABOLISM OF [H-3] S-(-)-COTININE IN THE GUINEA-PIG - DETERMINATION OF INVIVO URINARY METABOLITES BY HIGH-PERFORMANCE LIQUID-RADIOCHROMATOGRAPHY [J].

CUNDY, KC ;

CROOKS, PA .

XENOBIOTICA, 1987, 17 (07) :785-792

[6]

CUNDY KC, 1985, DRUG METAB DISPOS, V13, P658

[7]

CUNDY KC, 1984, THESIS U KENTUCKY CO

[8]

GORROD JW, 1975, ESSAYS TOXICOL, V6, P35

[9] FACTORS AFFECTING IN-VITRO METABOLISM OF R-(+)-NICOTINE AND S-(-)-NICOTINE BY GUINEA-PIG LIVER PREPARATIONS [J].

JENNER, P ;

GORROD, JW ;

BECKETT, AH .

XENOBIOTICA, 1973, 3 (09) :563-572

[10] SPECIES VARIATION IN METABOLISM OF R-(+)-NICOTINE AND S-(-)-NICOTINE BY ALPHA-C-OXIDATION AND N-OXIDATION IN-VITRO [J].

JENNER, P ;

GORROD, JW ;

BECKETT, AH .

XENOBIOTICA, 1973, 3 (09) :573-580

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