ANTIGENIC PROPERTY OF PEDIOCIN ACH PRODUCED BY PEDIOCOCCUS-ACIDILACTICI H

Pediocin AcH, a bacteriocin of Pediococcus acidilactici H, inhibits the growth of several food spoilage and pathogenic bacteria. The antigenic property of partially purified pediocin AcH was tested by immunizing mice and a rabbit. Pediocin AcH was not immunogenic in these animals as determined by immunoblotting even after conjugation to bovine serum albumin. The non‐immunogenic nature of pediocin AcH, its non‐toxicity to laboratory animals and its hydrolysis by gastric proteolytic enzymes may be considered favourably in its possible use as a food preservative. Copyright © 1990, Wiley Blackwell. All rights reserved