DESIGNS FOR MIXTURE AND PROCESS VARIABLES APPLIED IN TABLET FORMULATIONS

被引：12

作者：

DUINEVELD, CAA

SMILDE, AK

DOORNBOS, DA

机构：

[1] Research Group Chemometrics, University Centre for Pharmacy, University of Groningen, 9713 AW Groningen

来源：

ANALYTICA CHIMICA ACTA | 1993年 / 277卷 / 02期

关键词：

OPTIMIZATION METHODS; DESIGN CONSTRUCTION; MIXTURE VARIABLES; PHARMACEUTICALS; PROCESS VARIABLES;

D O I：

10.1016/0003-2670(93)80456-U

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Although there are several methods for the construction of a design for process variables and mixture variables, there are not very many methods which are suitable to combine mixture and process variables in one design. Some of the methods which are feasible will be shown. These methods will be compared in a design space consisting of three mixture variables and two process variables. This comparison will be made with criteria from the theory of optimal design and with the aid of experimental data.

引用

页码：455 / 465

页数：11

共 14 条

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AMEMIYA T, 1985, ADV ECONOMETRICS BAS

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