3-DIMENSIONAL FUNCTIONAL MAGNETIC-RESONANCE-IMAGING OF HUMAN BRAIN ON A CLINICAL 1.5-T SCANNER

被引：121

作者：

VANGELDEREN, P

RAMSEY, NF

LIU, GY

DUYN, JH

FRANK, JA

WEINBERGER, DR

MOONEN, CTW

机构：

[1] NIMH,CLIN BRAIN DISORDERS BRANCH,WASHINGTON,DC 20032

[2] NIH,OFF INTRAMURAL RES,LAB DIAGNOST RADIOL RES PROGRAM,BETHESDA,MD 20892

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1995年 / 92卷 / 15期

关键词：

D O I：

10.1073/pnas.92.15.6906

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Functional magnetic resonance imaging (fMRI) is a tool for mapping brain function that utilizes neuronal activity-induced changes in blood oxygenation, An efficient three-dimensional fMRI method is presented for imaging brain activity on conventional, widely available, 1.5-T scanners, without additional hardware. This approach uses large magnetic susceptibility weighting based on the echo-shifting principle combined with multiple gradient echoes per excitation. Motor stimulation, induced by self-paced finger tapping, reliably produced significant signal increase in the hand region of the contralateral primary motor cortex in every subject tested.

引用

页码：6906 / 6910

页数：5