AN ENANTIOMERICALLY PURE EPOXYORGANOLITHIUM REAGENT FOR THE SYNTHESIS OF OLIGO(TETRAHYDROFURANS) BY AN EPOXIDE-CASCADE REACTION

被引：17

作者：

KOERT, U

WAGNER, H

STEIN, M

机构：

[1] Fachbereich Chemie der Philipps Universität

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(00)78360-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantiomerically pure oligo(tetrahydrofurans) 17 and 18 have been prepared using an epoxide cascade reaction. The polyepoxide precursors 13 and 14 were synthesized using the enantiomerically pure epoxyorganolithium reagent 3. Thus, addition of 3 to the THF aldehyde 11 gave alcohol 12 with a high Cram selectivity of 95:5.

引用

页码：7629 / 7632

页数：4

共 25 条

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