DIASTEREOSELECTIVE REDUCTION OF AN ALPHA-KETO-ESTER DERIVED FROM (-)-8-PHENYLMENTHOL - A 4-STEP SYNTHESIS OF R-HALOSTACHINE ANALOG

被引：30

作者：

SOLLADIECAVALLO, A

BENCHEQROUN, M

机构：

[1] Laboratoire de Stéréochimie Organometallique associé au CNRS EHICS, 67008 Strasbourg

来源：

TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 11期

关键词：

D O I：

10.1016/S0957-4166(00)82014-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An efficient (80% total yield) 4-step synthesis of a 94% e.e. R-(-)-Halostachine analogue is described. The method offers the possibility to introduce various substituents onto the aromatic ring and various alkyl groups on the amine. A one-step and high yield (almost-equal-to 100%) conversion of esters into amides is presented.

引用

页码：1165 / 1171

页数：7

共 15 条

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