DIASTEREOSELECTIVE REDUCTION OF AN ALPHA-KETO-ESTER DERIVED FROM (-)-8-PHENYLMENTHOL - A 4-STEP SYNTHESIS OF R-HALOSTACHINE ANALOG

被引:30
作者
SOLLADIECAVALLO, A
BENCHEQROUN, M
机构
[1] Laboratoire de Stéréochimie Organometallique associé au CNRS EHICS, 67008 Strasbourg
关键词
D O I
10.1016/S0957-4166(00)82014-5
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
An efficient (80% total yield) 4-step synthesis of a 94% e.e. R-(-)-Halostachine analogue is described. The method offers the possibility to introduce various substituents onto the aromatic ring and various alkyl groups on the amine. A one-step and high yield (almost-equal-to 100%) conversion of esters into amides is presented.
引用
收藏
页码:1165 / 1171
页数:7
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