MAPPING OF THE TRICHOHYALIN GENE - COLOCALIZATION WITH THE PROFILAGGRIN, INVOLUCRIN, AND LORICRIN GENES

被引：19

作者：

FIETZ, MJ

ROGERS, GE

EYRE, HJ

BAKER, E

CALLEN, DF

SUTHERLAND, GR

机构：

[1] UNIV ADELAIDE, DEPT BIOCHEM, GPO BOX 498, ADELAIDE, SA 5001, AUSTRALIA

[2] ADELAIDE CHILDRENS HOSP INC, DEPT CYTOGENET & MOLEC GENET, ADELAIDE, SA 5006, AUSTRALIA

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 1992年 / 99卷 / 05期

关键词：

D O I：

10.1111/1523-1747.ep12667301

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The chromosomal location of the gene encoding the human hair follicle protein trichohyalin has been determined by in situ hybridization. The human gene has been localized to the region 1q21.1 - 1q.23 (probably 1q21.3) using a sheep trichohyalin cDNA probe. The genes encoding three other epithelial proteins, namely, profilaggrin, involucrin, and loricrin, are also located in the same region of chromosome 1, which, together with their similar gene and protein structures, suggests that the four proteins form a novel superfamily of epithelial structural proteins.

引用

页码：542 / 544

页数：3

共 38 条

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