EFFECTS OF 4-HYDROXYBUTYRIC ACID ON BIOSYNTHESIS OF AMINO ACIDS IN CENTRAL NERVOUS SYSTEM

被引：30

作者：

GODIN, Y

MARK, J

MANDEL, P

机构：

[1] Centre de Neurochimie du C.N.R.S, Institut de Chimie Biologique, De la Faculté de Médecine, Strasbourg

来源：

JOURNAL OF NEUROCHEMISTRY | 1968年 / 15卷 / 10期

关键词：

D O I：

10.1111/j.1471-4159.1968.tb06826.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

—The effect of 4‐hydroxybutyrate (GHB) on cerebral glucose metabolism has been studied. GHB increases the glucose level, decreases the lactate concentration and diminishes the incorporation of glucose carbon into glutamic acid, glutamine, aspartic acid and GABA in the brain of the rat in a state of general anaesthesia. The data reported here suggest that GHB interferes in the metabolism of glucose in brain. Copyright © 1968, Wiley Blackwell. All rights reserved

引用

页码：1085 / &

共 23 条

[1] EFFECTS OF NEUROTROPIC DRUGS ON GLUCOSE METABOLISM IN RAT BRAIN IN VIVO
BACHELARD, HS
LINDSAY, JR
[J]. BIOCHEMICAL PHARMACOLOGY, 1966, 15 (08) : 1053 - +
[2] DETERMINATION OF MALTASE AND ISOMALTASE ACTIVITIES WITH A GLUCOSE-OXIDASE REAGENT
DAHLQVIST, A
[J]. BIOCHEMICAL JOURNAL, 1961, 80 (03) : 547 - &
[3] DRAKONTIDES AB, 1962, J PHARMACOL EXP THER, V135, P275
[4] FISHBEIN WN, 1964, J BIOL CHEM, V239, P357
[5] COMPARATIVE EFFECT OF GAMMA-HYDROXYBUTYRATE AND PHENOBARBITAL ON BRAIN ENERGY METABOLISM
FLEMING, MC
LACOURT, S
[J]. BIOCHEMICAL PHARMACOLOGY, 1965, 14 (12) : 1905 - &
[6] ENTRY OF GLUCOSE CARBON INTO AMINO ACIDS OF RAT BRAIN AND LIVER IN VIVO AFTER INJECTION OF UNIFORMLY 14C-LABELLED GLUCOSE
GAITONDE, MK
DAHL, DR
ELLIOTT, KAC
[J]. BIOCHEMICAL JOURNAL, 1965, 94 (02) : 345 - &
[7] GIARMAN MJ, 1964, SCIENCE, V145, P583
[8] THE CHROMATOGRAPHY OF AMINO ACIDS ON ION EXCHANGE RESINS - USE OF VOLATILE ACIDS FOR ELUTION
HIRS, CHW
MOORE, S
STEIN, WH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1954, 76 (23) : 6063 - 6065
[9] HOLDEN JT, 1962, AMINO ACID POOLS ED, P722
[10] QUANTITATIVE BESTIMMUNG VON L(+)-MILCHSAURE MIT MILCHSAUREDEHYDROGENASE
HORN, HD
BRUNS, FH
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1956, 21 (02) : 378 - 380

← 1 2 3 →