CLONING AND SEQUENCE-ANALYSIS OF A HAMSTER LIVER CDNA-ENCODING A NOVEL PUTATIVE CARBOXYLESTERASE

被引：15

作者：

SONE, T ^{[1
]}

ISOBE, M ^{[1
]}

TAKABATAKE, E ^{[1
]}

WANG, CY ^{[1
]}

机构：

[1] MICHIGAN CANC FDN,DEPT CHEM CARCINOGENESIS,DETROIT,MI 48201

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY | 1994年 / 1207卷 / 01期

关键词：

CARBOXYLESTERASE; MICROSOMAL N; O-ACETYLTRANSFERASE; CDNA SEQUENCE; SERINE-ESTERASE; (HAMSTER LIVER);

D O I：

10.1016/0167-4838(94)90063-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A full-length cDNA encoding for a putative carboxylesterase was isolated from a hamster liver cDNA library. The cDNA consisting of 1911 base pairs contained an open reading frame of 1683 base pairs encoding for a polypeptide of 561 amino-acid residues, including 27 N-terminal amino-acid residues for signal peptide. The deduced amino-acid sequence of the cDNA is in 67% homology with the amino-acid sequence of rabbit form 2 carboxylesterase, which has not yet been cloned. It also had many structural features highly conserved among carboxylesterase isozymes.

引用

页码：138 / 142

页数：5

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