DYE-SENSITIZED PHOTOOXIDATION OF ESCHERICHIA COLI RIBOSOME

被引：18

作者：

GARVIN, RT

JULIAN, GR

ROGERS, SJ

机构：

来源：

SCIENCE | 1969年 / 164卷 / 3879期

关键词：

D O I：

10.1126/science.164.3879.583

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Chemical modification of ribosomes from Escherichia coli by oxidation in the presence of selected photosensitizing dyes causes a rapid loss of their amino acid-incorporating ability. By comparing the efficiency of dyes that sensitize the photooxidation of either guanine in ribonucleic acid or amino acid residues in proteins, inactivation of one or more functional ribosomal proteins is inferred.

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页码：583 / &

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