MEAN-FIELD TREATMENT OF LOCAL BINDING PROCESSES

被引:9
作者
DICERA, E
机构
[1] Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, Box 8231, St. Louis
关键词
D O I
10.1063/1.462589
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A mean-field treatment of ligand binding to a biological macromolecule containing multiple binding sites correctly describes the essential thermodynamic features involved in the effects observed locally at the level of individual sites. Equilibrium and steady state phenomena can be analyzed within a simple framework that is particularly useful in practical applications. Analysis of the complex electron binding properties of cytochrome aa3 reveals the origin of the negative electron binding capacity observed experimentally for cytochrome a.
引用
收藏
页码:6515 / 6522
页数:8
相关论文
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