B-CELL ACTIVATION

被引：19

作者：

DESIDERIO, SV

机构：

[1] The Johns Hopkins University School of Medicine, Baltimore, MD

来源：

CURRENT OPINION IN IMMUNOLOGY | 1992年 / 4卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0952-7915(92)90073-N

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Extraordinary progress has been made in refining our understanding of the B-cell antigen receptor complex, the role of protein-tyrosine phosphorylation as the key intermediary in immunoglobulin signal transduction, and in identifying candidate effectors of immunoglobulin-mediated signaling. In addition, the properties of a new group of G proteins may rekindle interest in older observations implicating such molecules as important in B-cell activation.

引用

收藏

页码：252 / 256

页数：5

相关论文

共 35 条

[1] DISTINCT INTRACELLULAR FATES OF MEMBRANE AND SECRETORY IMMUNOGLOBULIN HEAVY-CHAINS IN A PRE-B CELL-LINE [J].

BACHHAWAT, AK ;

PILLAI, S .

JOURNAL OF CELL BIOLOGY, 1991, 115 (03) :619-624

[2] SURFACE-IMMUNOGLOBULIN CROSS-LINKING ACTIVATES A TYROSINE KINASE PATHWAY IN B-CELLS THAT IS INDEPENDENT OF PROTEIN-KINASE-C [J].

BRUNSWICK, M ;

SAMELSON, LE ;

MOND, JJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (04) :1311-1314

[3] ANTIIMMUNOGLOBULIN STIMULATION OF LYMPHOCYTES-B ACTIVATES SRC-RELATED PROTEIN-TYROSINE KINASES [J].

BURKHARDT, AL ;

BRUNSWICK, M ;

BOLEN, JB ;

MOND, JJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (16) :7410-7414

[4] B-LYMPHOCYTE ANTIGEN RECEPTORS (MLG) ARE NON-COVALENTLY ASSOCIATED WITH A DISULFIDE LINKED, INDUCIBLY PHOSPHORYLATED GLYCOPROTEIN COMPLEX [J].

CAMPBELL, KS ;

CAMBIER, JC .

EMBO JOURNAL, 1990, 9 (02) :441-448

[5] IGM ANTIGEN RECEPTOR COMPLEX CONTAINS PHOSPHOPROTEIN PRODUCTS OF B29 AND MB-1 GENES [J].

CAMPBELL, KS ;

HAGER, EJ ;

FRIEDRICH, RJ ;

CAMBIER, JC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (09) :3982-3986

[6] PROTEIN TYROSINE PHOSPHORYLATION IN INDUCED IN MURINE LYMPHOCYTES-B IN RESPONSE TO STIMULATION WITH ANTIIMMUNOGLOBULIN [J].

CAMPBELL, MA ;

SEFTON, BM .

EMBO JOURNAL, 1990, 9 (07) :2125-2131

[7] TYROSINE PHOSPHORYLATION OF PHOSPHOLIPASE-C INDUCED BY MEMBRANE IMMUNOGLOBULIN IN LYMPHOCYTES-B [J].

CARTER, RH ;

PARK, DJ ;

RHEE, SG ;

FEARON, DT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (07) :2745-2749

[8]

DYMECKI SM, 1992, J BIOL CHEM, V267, P4815

[9] SPECIFIC EXPRESSION OF A TYROSINE KINASE GENE, BLK, IN B-LYMPHOID CELLS [J].

DYMECKI, SM ;

NIEDERHUBER, JE ;

DESIDERIO, SV .

SCIENCE, 1990, 247 (4940) :332-336

[10] TYROSINE PHOSPHORYLATION OF COMPONENTS OF THE B-CELL ANTIGEN RECEPTORS FOLLOWING RECEPTOR CROSS-LINKING [J].

GOLD, MR ;

MATSUUCHI, L ;

KELLY, RB ;

DEFRANCO, AL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (08) :3436-3440

← 1 2 3 4 →