PURIFICATION AND CHARACTERIZATION OF EIKENELLA-CORRODENS TYPE-IV PILIN

被引：13

作者：

HOOD, BL ^{[1
]}

HIRSCHBERG, R ^{[1
]}

机构：

[1] UNIV MISSOURI, SCH BIOL SCI, KANSAS CITY, MO 64110 USA

来源：

INFECTION AND IMMUNITY | 1995年 / 63卷 / 09期

关键词：

D O I：

10.1128/IAI.63.9.3693-3696.1995

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Eikenella corrodens is a gram-negative human pathogen associated with periodontal diseases and soft-tissue infections. Pilin was purified by association-dissociation and fast protein liquid chromatography; it had an apparent molecular mass of about 14.8 kDa and an N-terminal amino acid sequence reflective of type IV pilins. Antibodies to the purified protein reacted with pill on whole cells. This is the first report of purification of type IV pili/pilin from this organism. Other type IV pill are important virulence factors; we are currently investigating the biological role of pili in E. corrodens.

引用

页码：3693 / 3696

页数：4

共 37 条

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