EPIDERMAL RESERVOIR - THEORETICAL APPROACH

被引：54

作者：

HADGRAFT, J ^{[1
]}

机构：

[1] UNIV STRATHCLYDE,DEPT PHARMACEUT CHEM,GLASGOW G1 1XW,SCOTLAND

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1979年 / 2卷 / 5-6期

关键词：

D O I：

10.1016/0378-5173(79)90033-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Mathematical expressions have been derived to describe the rates of release of drugs forming a reservoiz in the stratum corneum. The different physicochemical constants incorporated into the expressions and their significance in the formation of a reservoir are discussed. Theoretical release curves are given which show how the oil/water partition coefficient of the drug affects the storage capacity of the stratum comeum. © 1979.

引用

页码：265 / 274

页数：10

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