BAKERS-YEAST REDUCTION OF ALPHA-(ACYLAMINO)ACETOPHENONES AND LIPASE-CATALYZED RESOLUTION OF 2-ACYLAMINO-1-ARYLETHANOLS

被引：25

作者：

IZUMI, T

FUKAYA, K

机构：

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1993年 / 66卷 / 04期

关键词：

D O I：

10.1246/bcsj.66.1216

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Enzymatic reduction of alpha-acylaminoacetophenones with fermenting baker's yeast afforded optically active (R)-2-acylamino-1-arylethanols. Furthermore, lipase-catalyzed resolution of the 2-acylamino-1-arylethanols using vinyl acetate as an acyl donor resulted in the formation of (S)-1-acetoxy-2-acylamino-1-arylethanols and (R)-2-acylamino-1-arylethanols.

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页码：1216 / 1221

页数：6

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