EFFECT OF CHRONIC RESTRAINT STRESS ON DENDRITIC SPINES AND EXCRESCENCES OF HIPPOCAMPAL CA3 PYRAMIDAL NEURONS - A QUANTITATIVE STUDY

被引：89

作者：

SUNANDA ^{[1
]}

RAO, MS ^{[1
]}

RAJU, TR ^{[1
]}

机构：

[1] NATL INST MENTAL HLTH & NEUROSCI,DEPT NEUROPHYSIOL,BANGALORE 560029,KARNATAKA,INDIA

来源：

BRAIN RESEARCH | 1995年 / 694卷 / 1-2期

关键词：

CHRONIC RESTRAINT STRESS; DENDRITIC SPINE; EXCRESCENCE; HIPPOCAMPUS;

D O I：

10.1016/0006-8993(95)00822-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Effect of chronic restraint stress on the number of dendritic spines and excrescences of hippocampal CA3 pyramidal neurons has been investigated. The results revealed a significant increase in the number of dendritic spines of apical and basal dendrites in rats subjected to restraint stress (6 h per day for 21 days). The number of excrescences were also markedly increased in stressed rats. The physiological significance and possible mechanism for increased spine density is discussed.

引用

页码：312 / 317

页数：6

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